Mar. 25, 2015 - Grand Rounds: “Metabolomic Profiling of Multiple Sclerosis”

Metabolomics is an emerging field of science that studies the collection of all metabolites in a biological system. Dr. Fozia Mir, Assistant Research Scientist at Tisch MS, presented a comprehensive overview of how metabolomic studies are currently being applied to MS research. Dr. Mir also presented her own exciting work describing the screening of metabolites in the cerebrospinal fluid from MS patients. Intriguingly, a number of metabolites were altered in different subsets of MS patients, highlighting several new metabolic pathways that may be altered during the disease. The identification of a unique metabolic fingerprint in MS may assist with diagnosis of progressive disease, as well as provide new therapeutic targets for treatment. 

Below is a schematic of the process used to profile metabolomics. 

Participation in this Grand Rounds event, hosted by the Tisch MS Research Center of New York, is a CME activity and is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.