In November 2011, Tisch MS was approved by the International Cellular Medicine Society (ICMS), an Institutional Review Board (IRB), to begin a phase I safety and tolerability trial of Mesenchymal Stem Cell-Derived Neural Progenitors in 20 selected Multiple Sclerosis patients. The Food and Drug...
The Tisch MS stem cell research team regrets to announce that the two major grant applications by which we had hoped to fund our proposed clinical trial of stem cell therapy in Multiple Sclerosis have not been approved. An application to the philanthropic arm of the Hearst Foundations was declined...
The Tisch MS Research Center of New Yorkis pleased to announce that it has successfully completed the initial steps towards accreditation to serve as a facility for the processing of human stem cells in clinical trials from the International Cellular Medicine Society. Along with soon-to-be-filed...
Deirdre Dulak (Tisch MS) presented the following article in Journal Club. Article Title : Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis Reference : G. Comi, D. Jeffery, L. Kappos, X. Montalban, A. Boyko, M.A. Rocca, and M. Filippi. (2012) The New England Journal of Medicine...
Fozia Mir, PhD, an Assistant Research Scientist at Tisch MS, presented a lecture on “Lipids in Multiple Sclerosis” Wednesday morning. Lipids are very biologically active compounds that are highly susceptible to oxidative damage due to the presence of double bonds. Oxidative stress can cause tissue...
Donald Lee (Tisch MS) presented the following article in Journal Club. Article Title : Inhibition of Fatty Acid Metabolism Ameliorates Disease Activity in an Animal Model of Multiple Sclerosis Reference : L.P. Shriver and M. Manchester. Sci. Rep. 1 , 79; DOI:10.1038/srep00079 (2011). Multiple...
Kristi Clark (Tisch MS) presented the following article in Journal Club. Article Title : The Encephalitogenicity of T(H)17 Cells is Dependent on IL-1- and IL-23-Induced Production of the Cytokine GM-CSF Reference : M. El-Behi, B. Ciric, H. Dai, Y. Yan, M. Cullimore, F. Safavi, G. Zhang, B. Dittel,...
Hannah Rosenthal (Tisch MS) presented the following article in Journal Club. Article Title : Neural Differentiation of Patient Specific iPS Cells as a Novel Approach to Study the Pathophysiology of Multiple Sclerosis Reference : B. Song, G. Sun, D. Herzszfeld, A. Sylvain, N. Campanale, C. Hirst, S...
Esther Jun (Tisch MS) presented the following article in Journal Club. Article Title : Polyglutamation of Methotrexate With Common Polymorphisms in Reduced Folate Carrier, Aminoimidazole Carboxamide Ribonucleotide Transformylase, and Thymidylate Synthase Are Associated With Methotrexate Effects in...
Hana Conlon (Tisch MS) presented the following article in Journal Club. Article Title : Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation Reference : A. Peters, L. Pitcher, J. Sullivan, M. Mittsdoerfer, S. Acton, B. Franz, K. Wucherpfennig, S. Turley, M...