Tisch MS News

Jerry Lin (Tisch MS) presented the following article in Journal Club. Article Title: Persistence of Epstein-Barr Virus in Self-Reactive Memory B Cells Reference: S.I. Tracy, K. Kakalacheva, J.D. Lünemann, K. Luzuriaga, J. Middeldorp, and D.A. Thorley-Lawsona. (2012) Journal of Virology. 86 (22):...

November 16, 2012

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Saud Sadiq, MD (Tisch MS, IMSMP) presented the following article in Journal Club. Article Title: Potassium Channel KIR4.1 as an Immune Target in Multiple Sclerosis Reference: R. Srivastava, M. Aslam, S.R. Kalluri, L. Schirmer, D. Buck, B. Tackenberg, V. Rothhammer, A. Chan, R. Gold, A. Berthele, J...

November 9, 2012

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Daniel Koffler (Tisch MS) presented the following article in Journal Club. Article Title : Decreased Hydrocortisone Sensitivity of T Cell Function in Multiple Sclerosis Associated Major Depression Reference : A. Fischer, C. Otte, T. Krieger, R. Nichols, S. Krüger, K. Ziegler, K. Schulz, C.Heesen,...

October 5, 2012

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The Food and Drug Administration (FDA) made an unannounced site visit to Tisch MS during the week of August 27 in connection with the proposed Tisch MS clinical trial of Mesenchymal Stem Cell-Derived Neural Progenitors (MSC-NPs). As noted in this space in August , the FDA had previously initiated...

September 13, 2012

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In November 2011, Tisch MS was approved by the International Cellular Medicine Society (ICMS), an Institutional Review Board (IRB), to begin a phase I safety and tolerability trial of Mesenchymal Stem Cell-Derived Neural Progenitors in 20 selected Multiple Sclerosis patients. The Food and Drug...

August 24, 2012

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The Tisch MS stem cell research team regrets to announce that the two major grant applications by which we had hoped to fund our proposed clinical trial of stem cell therapy in Multiple Sclerosis have not been approved. An application to the philanthropic arm of the Hearst Foundations was declined...

July 9, 2012

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The Tisch MS Research Center of New Yorkis pleased to announce that it has successfully completed the initial steps towards accreditation to serve as a facility for the processing of human stem cells in clinical trials from the International Cellular Medicine Society. Along with soon-to-be-filed...

April 23, 2012

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Deirdre Dulak (Tisch MS) presented the following article in Journal Club. Article Title : Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis Reference : G. Comi, D. Jeffery, L. Kappos, X. Montalban, A. Boyko, M.A. Rocca, and M. Filippi. (2012) The New England Journal of Medicine...

April 13, 2012

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Fozia Mir, PhD, an Assistant Research Scientist at Tisch MS, presented a lecture on “Lipids in Multiple Sclerosis” Wednesday morning. Lipids are very biologically active compounds that are highly susceptible to oxidative damage due to the presence of double bonds. Oxidative stress can cause tissue...

March 28, 2012

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Donald Lee (Tisch MS) presented the following article in Journal Club. Article Title : Inhibition of Fatty Acid Metabolism Ameliorates Disease Activity in an Animal Model of Multiple Sclerosis Reference : L.P. Shriver and M. Manchester. Sci. Rep. 1 , 79; DOI:10.1038/srep00079 (2011). Multiple...

March 23, 2012

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