Tisch MS News

A Statement on Stem Cell Trial Developments: August 24, 2012

In November 2011, Tisch MS was approved by the International Cellular Medicine Society (ICMS), an Institutional Review Board (IRB), to begin a phase I safety and tolerability trial of Mesenchymal Stem Cell-Derived Neural Progenitors in 20 selected Multiple Sclerosis patients. The Food and Drug...

August 24, 2012

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A Statement on Stem Cell Trial Funding: July 9, 2012

The Tisch MS stem cell research team regrets to announce that the two major grant applications by which we had hoped to fund our proposed clinical trial of stem cell therapy in Multiple Sclerosis have not been approved. An application to the philanthropic arm of the Hearst Foundations was declined...

July 9, 2012

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Stem Cell Trial Update: April 23, 2012

The Tisch MS Research Center of New Yorkis pleased to announce that it has successfully completed the initial steps towards accreditation to serve as a facility for the processing of human stem cells in clinical trials from the International Cellular Medicine Society. Along with soon-to-be-filed...

April 23, 2012

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Journal Club: April 13, 2012

Deirdre Dulak (Tisch MS) presented the following article in Journal Club. Article Title : Placebo-Controlled Trial of Oral Laquinimod for Multiple Sclerosis Reference : G. Comi, D. Jeffery, L. Kappos, X. Montalban, A. Boyko, M.A. Rocca, and M. Filippi. (2012) The New England Journal of Medicine...

April 13, 2012

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Grand Rounds: Wednesday, March 28, 2012

Fozia Mir, PhD, an Assistant Research Scientist at Tisch MS, presented a lecture on “Lipids in Multiple Sclerosis” Wednesday morning. Lipids are very biologically active compounds that are highly susceptible to oxidative damage due to the presence of double bonds. Oxidative stress can cause tissue...

March 28, 2012

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Journal Club: Friday, March 23, 2012

Donald Lee (Tisch MS) presented the following article in Journal Club. Article Title : Inhibition of Fatty Acid Metabolism Ameliorates Disease Activity in an Animal Model of Multiple Sclerosis Reference : L.P. Shriver and M. Manchester. Sci. Rep. 1 , 79; DOI:10.1038/srep00079 (2011). Multiple...

March 23, 2012

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Journal Club: Friday, March 9, 2012

Kristi Clark (Tisch MS) presented the following article in Journal Club. Article Title : The Encephalitogenicity of T(H)17 Cells is Dependent on IL-1- and IL-23-Induced Production of the Cytokine GM-CSF Reference : M. El-Behi, B. Ciric, H. Dai, Y. Yan, M. Cullimore, F. Safavi, G. Zhang, B. Dittel,...

March 9, 2012

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Journal Club: Friday, March 2, 2012

Hannah Rosenthal (Tisch MS) presented the following article in Journal Club. Article Title : Neural Differentiation of Patient Specific iPS Cells as a Novel Approach to Study the Pathophysiology of Multiple Sclerosis Reference : B. Song, G. Sun, D. Herzszfeld, A. Sylvain, N. Campanale, C. Hirst, S...

March 2, 2012

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Journal Club: Friday, February 24, 2012

Esther Jun (Tisch MS) presented the following article in Journal Club. Article Title : Polyglutamation of Methotrexate With Common Polymorphisms in Reduced Folate Carrier, Aminoimidazole Carboxamide Ribonucleotide Transformylase, and Thymidylate Synthase Are Associated With Methotrexate Effects in...

February 24, 2012

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Journal Club: Friday, February 17, 2012

Hana Conlon (Tisch MS) presented the following article in Journal Club. Article Title : Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation Reference : A. Peters, L. Pitcher, J. Sullivan, M. Mittsdoerfer, S. Acton, B. Franz, K. Wucherpfennig, S. Turley, M...

February 17, 2012

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