Nicolas Daviaud, PHD

Dr. Daviaud joined the Tisch MS Research Center of New York in January 2019, after completing his postdoctoral training at the Icahn School of Medicine at Mount Sinai. As a postdoctoral fellow, he studied the use of cerebral organoids as a new human model of preterm hypoxic injury, as well as the engraftment of transplanted human cerebral organoids in mouse cortex for neural repair in cases of brain injury or neurodegeneration.

Dr. Daviaud received his PhD in Neuroscience and his Master's Degree in Science Technology and Health Engineering at the University of Angers, France. His thesis work focused on the development and characterization of pharmacologically active microcarriers conveying stem cells for the treatment of neurodegenerative disorders.

Dr. Daviaud's research at Tisch MSRCNY is directed towards using cerebral organoids as a model of multiple sclerosis and as a new platform to study therapeutic approaches and analyze mechanisms involved in repair/regeneration of brain cells.

SELECTED ABSTRACTS

2022

• Mia DiCostanzo, Tara Edwards, Nicolas Daviaud, Saud Sadiq. Tisch Multiple Sclerosis Research Center of New York, New York, NY, USA. Disruption of Stem Cell Proliferation and Differentiation Capacity in a Cerebral Organoid Model of Multiple Sclerosis.

• Nicolas Daviaud, Saud A Sadiq. Cyclin-dependent kinase inhibitor p21 dysregulation induces oligodendrocyte differentiation impairment in multiple sclerosis cerebral organoids. 2022 Society for Neuroscience.

2021

• Eric Chen, Nicolas Daviaud, Saud A Sadiq, MD. Effect of patient with multiple sclerosis genetic backgroud on cell population in cerebral organoid model. Presented at the American Academy of Neurology (AAN) Annual Meeting held April 17-22, 2021

• Tara Edwards, Eric Chen, Nicolas Daviaud, Saud A Sadiq. Tisch Multiple Sclerosis Research Center of New York, New York, NY, USA. Cell Cycle Inhibitor p21 Expression Decrease In PPMS Cerebral Organoids Leads To Exhaustion Of The Progenitor Pool Independently Of Apoptosis Pathway

• Nicolas Daviaud, Eric Chen, Saud A Sadiq. Tisch Multiple Sclerosis Research Center of New York, New York, NY, USA. Analysis of distinct cell population fate in Patient-Derived Cerebral Organoid Model of Multiple Sclerosis.